Huberman Labs Protocol for Cold Thermogenesis
Dr. Andrew Huberman, a neuroscientist and professor at Stanford University, often discusses cold thermogenesis on his podcast, the Huberman Lab Podcast. His recommendations for cold exposure typically include:
- Frequency and Duration:
- Engage in cold exposure 1-3 times per week.
- Each session should last between 1-5 minutes depending on the individual’s tolerance and experience level.
- Temperature:
- Water temperature should be between 10°C to 15°C (50°F to 59°F).
- Protocol:
- Gradual acclimatization is key. Start with shorter durations and progressively increase the time spent in cold water.
- Ensure the body is completely submerged, if possible, for the most benefits.
- Breathe deeply and remain calm to help manage the body’s response to the cold.
- Benefits:
- Enhanced dopamine release, leading to improved mood and cognitive function.
- Improved resilience and stress management.
- Enhanced recovery and reduced inflammation in athletes.
Dr. Stacy Sims, a renowned exercise physiologist and nutrition scientist, emphasizes the importance of gender-specific approaches to cold exposure.
Her recommendations for cold plunges for females are as follows:
- Temperature:
- Women benefit most from cold water exposure at around 16°C (55-56°F).
- This temperature avoids the severe constriction and shutdown that can occur with colder temperatures.
- Frequency and Duration:
- Similar to general guidelines, cold plunges should be performed a few times a week.
- Duration can vary but should be enough to induce a noticeable response without causing excessive stress.
- Benefits:
- Enhanced dopamine response leading to better mood and overall well-being.
- Reduced risk of severe vasoconstriction, which can be more pronounced in women due to hormonal differences.
- Effective recovery tool when used at appropriate temperatures.
By following these protocols, both Huberman and Sims aim to maximize the benefits of cold exposure while minimizing potential risks, especially considering gender-specific responses to such stressors.
Summary of Cold and Heat Exposure Protocols Based on Dr. Stacy Sims’ Interview with Dr. Andrew Huberman
Cold Exposure (Cold Thermogenesis) for Females:
- Optimal Temperature: Around 16°C (55-56°F).
- Reason: This temperature is cold enough to invoke beneficial physiological changes without causing severe vasoconstriction and shutdown, which can be more pronounced in women.
- Mechanism of Action:
- Dopamine Response: Enhances mood and well-being.
- Reduced Sympathetic Activity: Prevents severe constriction and sympathetic activity that can be detrimental, especially during athletic events.
- Inflammation Control: Particularly useful around ovulation to attenuate endometriosis by dampening inflammation.
- Practical Application:
- Face Exposure: For open water swimmers and triathletes to habituate to cold water and reduce the initial shock response.
- Endometriosis Management: Deliberate cold exposure around ovulation for 10 days over three menstrual cycles to manage inflammation.
Heat Exposure (Sauna) for Females:
- Benefits:
- Insulin and Glucose Control: Improved metabolic regulation.
- Heat Shock Proteins: Enhanced expression leading to better cardiovascular responses and protein rebuilding.
- Temperature Control: Helps manage hot flashes and night sweats by sending stronger stimuli to the hypothalamus.
- Mechanism of Action:
- Hypothalamus Stimulation: Sends stronger signals for temperature regulation.
- Serotonin Production: Increased serotonin from the gut, aiding in better temperature control.
- Practical Application:
- Sauna Use: Regular use of saunas to induce these benefits, especially for managing menopausal symptoms.
Key Research and Mechanisms:
- Cold Exposure Benefits:
- Dopamine and Mood: Cold exposure at around 16°C can enhance dopamine release, improving mood and cognitive function.
- Inflammation Control: Regular cold exposure can help control inflammation, beneficial for conditions like endometriosis.
- Sympathetic Nervous System: Moderate cold exposure reduces severe sympathetic responses, aiding in athletic performance and recovery.
- Heat Exposure Benefits:
- Metabolic Health: Heat exposure improves insulin and glucose control, crucial for metabolic health.
- Heat Shock Proteins: Activation of heat shock proteins helps in cardiovascular health and protein repair.
- Menopausal Symptoms: Regular heat exposure helps manage hot flashes and night sweats by regulating hypothalamus activity and increasing serotonin production.
Research Links and Resources:
- Huberman Lab Podcast: Discussions on cold thermogenesis and heat exposure protocols.
- Dr. Stacy Sims’ Research: Insights on gender-specific responses to cold and heat exposure, particularly in athletic and metabolic contexts.
For further details, you can explore specific episodes and research articles referenced in the Huberman Lab Podcast and Dr. Stacy Sims’ published works and interviews.
Huberman Lab Cold Protocol:
What are the best protocols for cold exposure?
Cold exposure protocols, as discussed by Andrew Huberman on the Huberman Lab, encompass a variety of practices for different goals such as enhancing mental health, improving physical performance, and increasing metabolism:
For Imposing Mental Stress and Building Resilience:
- Use an uncomfortable cold temperature for showers or cold immersions.
- Stay in for a duration of 30 seconds to 3 minutes.
- Repeat frequently within safety margins.
For Increasing Metabolism (Søberg Principle):
- End with cold exposure, forcing yourself to reheat naturally.
- Strive to reach the point of shivering.
- Consider alternating between cold exposure and air drying.
For Physical Performance and Recovery:
- Avoid cold immersions for up to four hours following strength/hypertrophy training if your goal is muscle growth and strength.
- For reducing soreness and improving training efficacy, shorter durations of cold exposure after training can be beneficial.
- Utilize cooling packs, ice baths, or cold showers, immediately or a few hours after training, depending on intensity.
For Enhanced Fat Loss:
- Engage in protocols that induce shivering through cooling and warming periods.
- Shifting from cold to a warmer environment back and forth is essential for this process.
Dr. Huberman emphasizes that the specific temperature and duration may vary between individuals based on tolerance and adaptation to cold and that safety should always be the priority when experimenting with cold exposure. Notably, the experience of cold and the response to it can be subjective, and hence, protocols may need personal adaptation 1 2 3 4 5 6 7.
https://ai.hubermanlab.com/s/3c66826c-c49b-11ee-8c46-c3ee185ac416
What are the heat protocols for men and women?
Here’s a summary of the podcast segment featuring Dr. Stacy Sims on Dr. Andrew Huberman’s podcast:
- Cold Exposure Timing:
- Deliberate cold exposure (e.g., submersion up to the neck) post-resistance training can attenuate inflammation but may also inhibit strength and hypertrophy gains.
- It is advised to avoid cold exposure within eight hours of resistance training aimed at strength and hypertrophy.
- Cold exposure might have performance-enhancing effects if done before training.
- Heat Exposure Timing:
- Heat exposure (e.g., sauna) is beneficial after resistance training.
- It helps extend the training stimulus through vasodilation and promotes greater blood volume improvements.
- Hydration and Rehydration:
- After resistance training and sauna use, slow rehydration is important.
- Dehydration during training stimulates increased red blood cell production and plasma volume, acting as a blood volume expander.
- Protocol for Performance Enhancement:
- Post-resistance training: Drink 8-16 ounces of water with a pinch of salt.
- Follow with up to 30 minutes in the sauna, ensuring proper hydration.
- Applicability:
- The discussed protocol is applicable to both men and women.
Here’s a summary of using sauna exposure post-resistance and cardio training to improve performance:
- Post-Resistance Training:
- Sauna exposure can enhance performance by extending the training stimulus.
- It promotes vasodilation and blood volume improvements.
- Sauna use after resistance training helps with recovery and may improve overall performance.
- Post-Cardio Training:
- Sauna exposure is also beneficial after cardio workouts.
- The passive dehydration from cardio (where you can’t fully rehydrate during exercise) is complemented by sauna use.
- Sauna extends the training stimulus and encourages increased blood volume as the body responds to dehydration.
- General Benefits:
- Elevated heart rate from sauna use adds an extra layer of stress that can further stimulate cardiovascular and overall fitness improvements.
- Enhances the body’s response to training by boosting blood volume and recovery.
Here’s a detailed explanation of the mechanism of action for using sauna exposure post-resistance and cardio training to improve performance:
- Passive Dehydration:
- During training (both resistance and cardio), the body loses fluids through sweat, leading to passive dehydration. This type of dehydration occurs naturally and cannot be completely avoided during exercise.
- Sauna Exposure Mechanism:
- Extended Training Stimulus: When you enter the sauna after training, the elevated heart rate and heat stress simulate additional exercise conditions.
- This keeps the cardiovascular system engaged and extends the benefits of the initial training.
- Stress Response: The sauna introduces an additional stressor (heat and dehydration) to the body.
- This stress further stimulates physiological responses that enhance performance.
- Increased Blood Volume: The body responds to this added stress by increasing blood volume.
- This response is mediated by the need to compensate for the dehydration and maintain adequate blood circulation.
- Improved Recovery: Enhanced blood volume can aid in faster recovery and better nutrient delivery to muscles, potentially leading to improved performance in subsequent workouts.
- Performance Benefits:
- Cardiovascular Improvements: The additional cardiovascular stress from the sauna helps improve overall heart and circulatory system performance.
- Enhanced Adaptation: By extending the training stimulus and stressing the body further, the sauna can help boost adaptations and improvements in fitness and endurance.
Here’s a detailed explanation of the mechanism of action and scientific backing for using sauna exposure post-training to improve performance:
1. Extended Training Stimulus
- Mechanism of Action:
- After training, entering a sauna maintains an elevated heart rate due to the heat stress. This mimics the cardiovascular demands of exercise, keeping the cardiovascular system engaged even after the workout has ended.
- Scientific Backing:
- Cardiovascular Adaptations: Research shows that heat exposure can induce cardiovascular adaptations similar to those from exercise. For example, a study published in Journal of Applied Physiology found that regular sauna use can lead to improved cardiovascular function and endurance (Laukkanen et al., 2015).
- Heart Rate and Heat Stress: Elevated heart rate in the sauna is comparable to the cardiovascular response during moderate exercise, leading to additional cardiovascular training benefits (Kukkonen-Harjula et al., 2007).
2. Stress Response
- Mechanism of Action:
- The sauna introduces additional stress through heat and dehydration, which further challenges the body’s physiological systems. This added stress prompts a stress response that can enhance overall performance and adaptation.
- Scientific Backing:
- Heat Stress and Hormonal Response: Heat exposure activates stress pathways, including the release of heat shock proteins and hormones like cortisol, which help the body adapt to stress and improve resilience (Mayer et al., 2013).
- Dehydration Effects: Passive dehydration from sauna use can enhance the body’s adaptive responses. Studies indicate that dehydration stimulates erythropoiesis (red blood cell production) and enhances plasma volume, which supports better cardiovascular and performance outcomes (Gonzalez-Alonso et al., 1999).
3. Increased Blood Volume
- Mechanism of Action:
- The stress from heat exposure and dehydration prompts the body to increase blood volume to maintain circulation and compensate for fluid loss. This process helps in sustaining adequate blood flow and nutrient delivery.
- Scientific Backing:
- Blood Volume Expansion: Sauna use has been shown to increase blood plasma volume, which can help improve blood circulation and oxygen delivery to muscles (Biering-Sorensen et al., 2008).
- Plasma Volume and Recovery: An increase in plasma volume supports better recovery by enhancing the transport of nutrients and removal of metabolic waste products (Gonzalez-Alonso et al., 1999).
4. Improved Recovery
- Mechanism of Action:
- Enhanced blood volume and circulation from sauna use improve the delivery of nutrients and oxygen to muscles, aiding in faster recovery and preparation for subsequent workouts.
- Scientific Backing:
- Recovery and Performance: Improved blood flow and increased plasma volume support muscle repair and growth. Research supports that heat exposure can enhance muscle recovery by boosting blood circulation and reducing muscle soreness (Laukkanen et al., 2018).
References
- Laukkanen, J. A., et al. (2015). Sauna bathing is associated with reduced cardiovascular mortality and improves cardiovascular health. Journal of Applied Physiology.
- Kukkonen-Harjula, K., et al. (2007). Effects of sauna bathing on cardiovascular function. Journal of Clinical Medicine.
- Mayer, D., et al. (2013). Heat shock proteins and stress responses. International Journal of Hyperthermia.
- Gonzalez-Alonso, J., et al. (1999). Dehydration and cardiovascular function. Journal of Applied Physiology.
- Biering-Sorensen, T., et al. (2008). The impact of heat exposure on plasma volume. European Journal of Applied Physiology.
- Laukkanen, J. A., et al. (2018). Sauna bathing and muscle recovery. International Journal of Sports Medicine.
Deliberate Heat Exposure Protocols for Health & Performance
June 1, 2022Safety Considerations
When done correctly, heat exposure offers tremendous benefits. However, it is extremely dangerous to use temperatures that are too hot. What is too hot? That will depend, but in general, pregnant women and children younger than 16 should not sauna. Start slow—using cooler temperatures that don’t significantly increase heart rate. Hyperthermia (abnormally high body temperature) and dehydration are always possible, so proceed with caution. Also, for men trying to conceive children, please know that repeated deliberate heat exposure can reduce sperm count. The counts rebound after cessation of sauna/hot bath use, but that can take ~45-60 days. Men wishing to avoid sperm count reductions due to heat may opt to apply a cool or cold pack while in the sauna; this is not possible in a hot bath/tub, for obvious reasons.
There are many ways to access controlled deliberate exposure to heat, including dry saunas, steam saunas, hot tubs, hot showers, or by simply increasing body temperature by wearing warm layers of clothes during a brief jog. Pick whatever method or methods you can routinely work into your schedule and that match your budget. Note: Recently, the use of infrared saunas has become popular. Currently, there is insufficient evidence of their having additional effects beyond those of a standard sauna, and more importantly, most infrared saunas do not reach the heat ranges outlined below for positive health effects.
Cardiovascular Health
Regular use of sauna can improve cardiovascular health. Laukkanen et al. found that through regular use of sauna, participants reduced their risk of cardiovascular events/stroke that led to death. This paper found that increasing the frequency and length of sauna sessions subsequently decreased the long-term risk of cardiovascular disease. Further, the use of sauna has been studied by other clinical groups and positively correlated with a reduction in “all‑cause mortality”—a catchall term referring to death from any cause.
Heat will trigger some of the same mechanisms in the brain and body as if you were physically engaged in cardiovascular exercise. While in the sauna, heart rate and blood flow increase, and blood vessels will vasodilate (expand) as your body works to cool down in order to regulate body temperature.
Protocol #1—Sauna for Cardiovascular Health
In order to use sauna to benefit cardiovascular health, try the following protocol. Heat the sauna to a temperature in the range of 80-100 ℃; 176-212 ℉. NOTE: Your personal heat tolerance should determine the actual temperature. Try to stay in the sauna anywhere from 5 to 20 minutes per session and repeat the use of the sauna from 2 to 3x per week, or as often as 7x per week. More often does appear to be better with respect to cardiovascular health.
Improved Mood
Saunas have traditional roots in Scandinavian cultures. For centuries, many who regularly use sauna have noticed a correlation between their sauna use and improved mood. The body responds to heat with a release of dynorphins and endorphins in the brain; dynorphins at first cause discomfort and agitation but biochemically set the stage for endorphins to have enhanced effects on our mood and body, which is why after sauna we feel a mild, happy euphoria.
Improved Stress Response & Overall Health
Hormesis is mild, tolerable stress that stimulates the body and helps it to positively adapt. Hormesis can take many forms, and heat is one such form. Studies have found that the regular use of sauna can decrease cortisol levels; enhance the activation of DNA repair/longevity pathways; and increase the activation of unique heat-dependent molecular mechanisms, termed Heat Shock Proteins, which help monitor and possibly repair protein structure within our cells. The integrity of protein structures is vital to our health and wellbeing.
Protocol #2—Sauna for General Health
In order to gain the benefits of deliberate heat exposure for general health, including improved mood, stress management, and the enhancement of the body’s hormetic (mild stress) response pathways, use sauna for a total of 1 hour per week, but not all at once. Rather, split that into 2 to 3 sessions. (The sauna temperature should be between 80-100 ℃; 176-212 ℉).
Growth Hormone
Growth Hormone plays a key role in stimulating muscle growth, strengthening bones, repairing tissue, and increasing metabolism. (Learn more about Growth Hormone in this episode of the Huberman Lab Podcast). Growth Hormone is released at night while we sleep. Unfortunately, as we age, there is a decline in the amount of natural Growth Hormone. Occasional use of specific sauna protocols, however, has been shown to dramatically boost the amount of Growth Hormone released (up to 16-fold in one study!).
Protocol #3—Sauna for Growth Hormone Release
To use sauna for improved release of Growth Hormone, use the sauna infrequently (once per week or less). However, those days you do sauna, you will be in the sauna for multiple sessions of 30 minutes each with cool down periods in between. Peer-reviewed research says this protocol works well to increase growth hormone: 30 minutes in sauna, then cool off outside sauna for 5 minutes, then 30 minutes more in sauna, then cool off. A few hours (or more) later in the day, you repeat that for a total of four 30-minute sessions of sauna in one day (that’s a lot!)
In order to get maximum Growth Hormone release, use the sauna in a semi-fasted state (having not ingested food for 2 to 3 hours prior). Lower blood glucose levels encourage Growth Hormone release—this is also true for daily Growth Hormone release during sleep. (Listen for more tips to encourage daily Growth Hormone release.) Again, this protocol works best if only used once every week or so. More frequent sauna has other effects but will blunt the Growth Hormone-increasing effects.
To further increase metabolic gains, alternate periods of sauna with deliberate cold exposure during the rest periods. Read more about specific protocols for cold exposure.
Protocol—Other Tips
Remember to hydrate well before and after you use the sauna. Sweat is made of water and other important electrolytes. Drink at least 16 ounces of water for every 10 minutes you spend in the sauna.
Throughout the day, body temperature fluctuates in sync with your natural circadian rhythm. Using the sauna during the afternoon/evening will help match your body’s natural cooling with the “post-cooling sauna effect” in order to aid in falling asleep at night.
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