How should aging female athletes fuel and train to improve performance and body composition?
Let’s do a deep dive into Dr. Stacy Sims interviews and blogs.
Dr. Stacy Sims on MBG podcast Summary

Dr. Stacy Sims on PERI-MENOPAUSE:
- Changes in ratio of Estrogen and Progesterone impacts all systems of the body
- Microbiome changes
- Recovery
- Body Composition
- Brain +Neurotransmitters
- Sleep architechture
- Hormones changing – now I need to find an external stress that is going to cause an ADAPTATION the way the hormones used to support
- Polarize high intensity training and heavy lifting
- Dropping the volume and adequate recovery
- Creating a stress to stimulate growth hormone
- Epigenetic changes in muscle to help with blood glucose control and glucose homeostasis
- Signal central nervous system to maintain power, speed and lean mass
Dr. Stacy Sims on POST MENOPAUSE:
Early menopause – 5 to 6 years after the one day in time of MENOPAUSE
- Lift heavy
- Sprint interval training 2-3 x week
- Limit or decrease lower intensity exercise with high volume (less is more)
Late menopause- 6 years after the one day in time MENOPAUSE
We don’t respond as well to the high intensity work
- Solution – more regular doses of sprint intervals but not more volume- shorter doses
- SIT 4 days of 15 minute intervals
- We lost sensitivity to estrogen or progesterone without the receptors around
- To keep lean mass, blood pressure in check, vascular, bone strength, cognition, and proprioception
- More play early post menopause but later post menopause we need to do SIT daily but short dose.
- more; regular, shorter doses of SPRINM interval training as we have lost sensitivity and loss of receptors
- Example 4 x 20 second sprints instead of 10 … upper intensity focus
Sprint Interval Training
- Central nervous system response – fast muscle contraction, neural pathways and avoid cognitive decline
- Glycolytic fuel- ATP CP and carbohydrate use for fueling
- More GLUT4 transporters- gate to allow glucose to come into cell without insulin = maintain glucose homeostasis as we are more insulin resistant as we age
- Cross talk with exerkines – deep abdominal fat and skeletal muscle via messengers – need carb in the muscle and not deep ab fat
- Proprioception – fall risk decreases
- Not the long slow distance endurance training
- Push RPE 9/10 and no more than 30 seconds, recovery back to Zone 1
- Fast Twitch muscle fibers
Zone Two for women?
- Research is based on male studies
- Women already have a larger amount of slow twitch fiber- oxidize fat better
- Women have less fast twitch muscle fibers than men
- Born XX – greater mitochondria density, mitochondrial respiration and greater sensitivity to metabolites that inhibits free fatty acids that come into cell
- Women are already very good at taking lactate, recycling it to use as fuel in aerobic metabolism
- Benefits of ZONE TWO– mitochondria health, increasing oxidative capacity, increasing mitochondrial health, increasing the number of MCT1 Transport Proteins
- MCT1 Transport proteins take lactate out of circulation then put them into mitochondria to get the lactate into circulation and be used as fuel
- MEN do need to increase the MCT1 to increase mitochondria health, mitochondrial respiratory capacity and slow twitch muscle fiber
- MCT1 – put lactate into circulation and out to use as fuel
- Men don’t have the same response as women do = difference between the exercise intensity = women need to do more high intensity work as they have less glycolytic muscles = we need to stimulate lactate production and regulate the ability to produce it then clear it
- if women don’t improve by doing sprint training -and spend too much time in Zone 2 ‘long slow distance’ – stuck being slow
- Men need more Zone Two training than women
- The exercise intensity – women need more HIIT as less glycolytic muscles or stuck in slow pace
- Sprint work and HIIT in women vs. men = women upregulate more MC1
- The exercise intensities- women need more HIGH intensity to stimulate lactate, to produce it and clear it …less SLOW MO workouts than what men need
- Women need to change how they fuel and train to get their desired improvements
Dr. Stacy Sims on Women and Zone 2 Summary Notes
- Zone 2 training is often promoted as a low-intensity, steady exercise (60-70% max heart rate) beneficial for endurance and metabolic health, but its benefits are overstated for women.
- Women naturally have a higher proportion of Type 1 slow-twitch fibers, which are efficient at fat oxidation and have higher mitochondrial density compared to men. This means women already excel at using fat as fuel during exercise.
- Metabolic flexibility—the ability to switch between fat and carbohydrate for energy—is also naturally higher in women, making additional Zone 2 training less critical for improving this aspect.
- Women store more intramuscular fat and have better fat metabolism due to higher levels of fat transporter proteins (CD36) and greater sensitivity to metabolic inhibitors like malonyl-CoA, making them less dependent on carbohydrate during exercise.
- Lactate production and clearance: Women produce less lactate during exercise compared to men, who rely more on Type 2 fibers and carbohydrate metabolism. Men upregulate lactate transporter proteins (MCT-1) more, but women’s bodies don’t require the same adaptations due to lower glycolytic activity.
- While Zone 2 training can be useful for active recovery, base-building, and lower-intensity days, women benefit more from high-intensity interval training (HIIT) or sprint work to stimulate mitochondrial and metabolic adaptations.
- A key problem for women is often training in a “gray zone” that’s harder than true Zone 2 but not intense enough for real gains, leading to fatigue without performance improvement.
- For women, focusing too much on long, steady-state exercise can result in being “stuck slow”. High-intensity sessions are more effective for stimulating lactate clearance, maintaining lean muscle mass, and enhancing performance.
- When doing Zone 2, women should ensure it’s truly easy and conversational, avoiding the tendency to work harder than necessary.
- https://www.drstacysims.com/blog/what-women-need-to-know-about-zone-2-training
Dr. Stacy Sims Summary on Training
Zone 2 Training Isn’t the Same for Women: Here’s a Better Approach
In one of her blogs, she broke down why Zone 2 training—touted online as the go-to for health, longevity, and performance—doesn’t benefit women the same way it does men. Let’s now explore what type of training actually works best for women.
A Quick Recap:
Zone 2 involves relatively easy, prolonged exercise (60-70% max heart rate for 45+ minutes) that feels sustainable for hours. The popular recommendation is to focus 3-4 weekly sessions on Zone 2 to enhance mitochondrial function, fat metabolism, and metabolic flexibility, while improving lactate clearance during higher-intensity exercise.
However, as discussed previously, prioritizing Zone 2 training may not be the ideal way for women to optimize mitochondrial function or lactate clearance. In fact, research suggests a different approach to training intensity is more effective for women.
The Science Behind It: MCT1 and MCT4
MCTs (MonoCarboxylate Transporters) are proteins that shuttle lactate and pyruvate across cell membranes. During intense exercise, skeletal muscles produce lactate, which isn’t just waste—it’s a fuel source that can be used by muscle and heart mitochondria. MCT1 pulls lactate into cells, while MCT4 moves it out of cells.
Research shows that exercise intensity impacts the expression of MCT1 and MCT4, but the response differs between men and women.
- In men, MCT1 increases regardless of exercise intensity, and MCT4 increases with repeated sprint intervals.
- In women, low-intensity training shows minimal increases in either transporter, but sprint interval training (SIT) increases MCT1 expression more effectively than lower-intensity exercise.
This difference is likely due to the lower glycolytic capacity in women compared to men and the influence of estrogen on MCT1 expression.
What Should Women Focus On?
For health and longevity, the goal should be to improve both mitochondrial function and glycolytic capacity, which supports brain resilience and may help prevent cognitive decline. Research indicates that at least three days a week of high-intensity interval training (HIIT) or sprint interval training (SIT) significantly increases MCT1 expression and enhances brain glycolysis, promoting better cognition and potentially preventing Alzheimer’s disease.
From a performance perspective, HIIT and SIT are crucial for boosting lactate production and clearance, while also building fast-twitch Type II fibers—which women have fewer of compared to slow-twitch Type I fibers. This translates to increased power and speed.
What About Endurance Athletes?
If you’re an endurance athlete, you still need long, slow training to build the capacity for long-distance events. However, spending too much time in Zone 2 won’t improve mitochondrial function and oxidative capacity in women the same way it does for men.
Interestingly, research has shown that while men need long, slow aerobic work to improve mitochondrial function, women naturally have better mitochondrial density and respiration. By integrating high-intensity work into your long training sessions, you can enhance both mitochondrial capacity and anaerobic capacity.
Conclusion:
If you’re not an endurance athlete, don’t be misled by the hype around Zone 2 training. Just because it’s trending doesn’t mean it’s the best approach for everyone—especially women. This highlights the importance of recognizing that women are not simply smaller versions of men, and training strategies should be tailored accordingly.
By mixing in specific high-intensity work, women can maximize their training benefits in a way that better suits their physiology.
What about carbohydrates? Summary…
Want to Avoid Low Energy Availability (LEA) and Relative Energy Deficiency in Sport (RED-S)? Eat Enough Carbohydrates
As fasting, keto, and carb-restriction gain popularity on social media, we’re seeing a troubling rise in low energy availability (LEA) among athletes. In my experience, around 55% of individuals who train daily fall into LEA, with women being particularly vulnerable.
What is LEA? LEA occurs when you’re not eating enough to cover both your basic metabolic needs and the energy you expend during exercise. If left unchecked, it can lead to serious health issues, such as a dangerous drop in bone mineral density.
How to Calculate Energy Availability (EA): To avoid LEA, ensure you’re eating enough to maintain energy availability (EA). EA is calculated as: Dietary Energy Intake (kcal) – Exercise Energy Expenditure (kcal), divided by Fat-Free Mass (FFM) in kilograms (kg).
- Aim for an EA of 45+ kcal/kg of FFM. If you train regularly, 50 kcal/kg of FFM is a great target.
- An EA of less than 30 kcal/kg is classified as LEA, and health risks can begin after just five days.
However, beyond just total calorie intake, it’s crucial to focus on carbohydrate consumption, particularly for women.
The Importance of Carbohydrate Intake
Current research highlights that many athletes, especially women, aren’t consuming enough carbohydrates. This creates low carbohydrate availability (LCA), which exacerbates the health and performance issues caused by LEA.
What is Low Carbohydrate Availability (LCA)? LCA occurs when your body doesn’t get enough carbohydrates to meet energy demands during exercise. The International Society of Sports Nutrition’s Female Athlete Position Stand emphasizes that consuming enough carbohydrates is essential to prevent LEA.
- Endurance athletes need 4.5 to 7 grams of carbs per kilogram of body weight per day.
- Women doing moderate training or short, intense sessions (e.g., CrossFit) require 3.5 to 5 grams of carbs per kilogram of body weight daily.
Yet, research shows that many women fall short of these recommendations. A study found that nearly half of young female athletes and a third of elite female athletes consume less than 4 g/kg of carbs per day. Across various sports, 45 to 98% of female athletes may not be meeting their carbohydrate needs.
Why Women are Particularly Sensitive to Low Carbohydrate Intake
Women are more sensitive to low nutrition, especially carbohydrates. When carbohydrate intake is insufficient, it reduces the expression of kisspeptin, a neuropeptide that regulates sex hormones and reproductive function. Kisspeptin also plays a role in glucose regulation, appetite control, and body composition.
Low kisspeptin levels can:
- Increase appetite
- Decrease energy expenditure
- Lower glucose-stimulated insulin secretion
Prolonged LCA can lead to numerous performance and health issues, including:
- Decreased endurance and muscle strength
- Impaired glycogen stores
- Poor concentration and coordination
- Increased injury risk
- Depression and irritability
For those trying to build lean muscle or improve sprint performance, LCA also hinders the body’s ability to make necessary adaptations, largely by increasing the oxidation of branched-chain amino acids (BCAAs), which are crucial for muscle growth and repair.
How to Prevent LCA and Maintain Optimal Energy Availability
1. Fuel for the Work Required:
Ensure you consume enough carbohydrates based on your upcoming training session. After a workout, aim to replenish your glycogen stores as quickly as possible.
- After prolonged exercise, consume at least 1.2 grams of carbs per kg of body weight and 0.38 grams of protein per kg.
- For peri- and post-menopausal women, consume this within 30 to 40 minutes to take advantage of non-insulin-dependent glycogen synthesis.
2. Eat Balanced Meals with Protein and Carbs:
At each meal, aim to include around 25% of your daily carbohydrate needs along with 35-40 grams of protein. For athletes with double training sessions, make sure to have a carbohydrate-rich snack (~30g) before the second session.3. Maintain a Balanced Nutrition Strategy:
From breakfast to dinner, ensure you’re fueling your body with a mix of carbs and protein to promote recovery and health. Stop eating about two hours before bed to support optimal digestion and recovery.By fueling appropriately throughout the day and tailoring carbohydrate intake to your activity level, you can avoid both LEA and LCA, and achieve better performance, adaptations, and overall health.
https://www.drstacysims.com/blog/restricting-carbs-hurts-performance-and-health
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