The doctor said my blood chemistry labs were “normal”…

But I am still struggling with fatigue, weight gain and symptoms of a sluggish metabolism.

I want to be OPTIMAL…not normal based on the average unhealthy sick.

Chronic stress impacts the WHOLE you…including your gut health, hormones, and liver detox pathways!

Check out your Full Thyroid Results against FUNCTIONAL ranges or OPTIMAL! Then we correlate data together and work on the whole person- inside and out to figure out the WHY.

High cortisol levels from chronic stress
have been associated with higher TSH
levels, which is a sign that your thyroid is
struggling to produce enough thyroid
hormone. The more stressed you are, the
harder time your body will have
converting T4 to T3, giving your body less
thyroid hormone to aid in important
functions like regulating your
metabolism—an important factor in the
link between thyroid dysfunction and
weight gain. And when stress is chronic,
you can in turn develop high Reverse T3,
a hormone that blocks the use of T3,
again making it harder for your body to
regulate these essential processes.
Identifying the root cause of thyroid
dysfunction will help you eliminate related
symptoms and get back to feeling your best.
If any of the symptoms discussed sound
familiar to you, talk to your doctor about
testing your thyroid, but most importantly,
make sure your testing is in depth. Here at
Parsley, we not only test for Thyroid
Stimulating Hormone (TSH), but in addition
we look at various T3 and T4 levels, antithyroglobulin, anti-TPO antibodies,
inflammatory markers, vitamin D and other
nutritional deficiencies associated with
thyroid disorders. Then, we determine the
best course of action for you. If you’re
suffering from a thyroid disorder, starting
with these lifestyle changes will set you on
the path to better thyroid health.
Proper thyroid function depends on key nutrients for
the production of T4 and the conversion of T4 to T3,
which is the thyroid hormone that is active on the
cellular level. If you’re not able to get enough of
nutrients like iodine, zinc, selenium, vitamin D, and
iron from food alone, you may want to talk to your
doctor about supplementing. A blood panel can
help you determine if you’re getting enough of
these nutrients
-Parsley Health

Thyroid Panel	Results		Analysis	Functional Range	Symptoms
TSH	2.07	1.82	High	0.5 – 2.0 µIU/mL	Slightly high
Total T4	5.70		Low	6.0 – 11.9 µg/dL
Free T4	1.20	1.12	Low	1.4 – 1.8 ng/dL	Low
Total T3	80.00	69.00	Low	120 – 180 ng/dL
Free T3 (bioactive)	2.40	2.20	Low	3.4 – 4.4 pg/mL	Very low – fatigue, brain fog, weight gain, low libido, hair loss, constipation, cold intolerance
T3 Uptake	25.00		Low	28 – 38%
Reverse T3	13.60		Normal	< 15 ng/dL
TPO Antibody (Thyroid Peroxidase Ab)	1.00		Normal	< 10 IU/mL
TBG Antibody (Thyroglobulin Ab)	8.00		Normal	< 20 IU/mL
TT3/RT3 Ratio				10 – 14
Free T3/RT3 Ratio				20 – 30

I want to be OPTIMAL…not normal based on the average unhealthy sick person.

Check out your Full Thyroid Results against FUNCTIONAL ranges or OPTIMAL! Then we correlate data together and work on the whole person- inside and out to figure out the WHY.

High cholesterol doesn’t mean heart disease… it could also corelate with

Hypothyroidism
Chronic bacterial and viral infections (especially H pylori)
Adrenal cortical dysfunction
Cardiovascular disease / Atherosclerosis
Biliary stasis / Fatty liver
Insulin resistance
Poor metabolism and utilization of fats
Early stage hyperglycemia/Diabetes/Metabolic Syndrome
Multiple Sclerosis

High triglycerides could relate to…

• Early stage hyperglycemia / Diabetes / Metabolic Syndrome
• Fatty liver / Liver congestion
• Insulin resistance
• Cardiovascular disease / Atherosclerosis
• Poor metabolism and utilization of fats
• Hypothyroidism
• H pylori infection
• Adrenal cortical dysfunction
• Alcoholism
• Oral contraceptives

High LDL Cholesterol could relate to…

• Diet high in refined carbohydrates
• Metabolic Syndrome
• Atherosclerosis
• Hyperlipidemia / Fatty Liver
• Oxidative stress
• Hypothyroidism
• H pylori infection

How does your Lipid panel correlate with Hypo or Hyper Thyroid issues?

Functional medicine is an approach that addresses the underlying causes of disease and focuses on promoting optimal function of the body’s systems.

In the context of hypothyroidism (underactive thyroid), there are several ways in which it may be related to high cholesterol and triglyceride levels.

Metabolism Regulation: Thyroid hormones play a crucial role in regulating the body’s metabolism, including the metabolism of fats and cholesterol. When thyroid function is impaired (hypothyroidism), the metabolic rate decreases, leading to a potential imbalance in lipid metabolism. This can result in elevated levels of cholesterol and triglycerides.
Low Thyroid Hormones Impact Lipid Clearance: Thyroid hormones influence the activity of enzymes responsible for breaking down and clearing cholesterol from the bloodstream. In hypothyroidism, the reduced levels of thyroid hormones can impair this clearance process, leading to an accumulation of cholesterol and triglycerides.
Insulin Resistance: Hypothyroidism has been associated with insulin resistance, a condition where cells in the body are less responsive to the effects of insulin. Insulin resistance can contribute to dyslipidemia (abnormal levels of lipids in the blood), including elevated triglycerides.
Inflammation and Oxidative Stress: Hypothyroidism can be associated with increased inflammation and oxidative stress in the body. Chronic inflammation and oxidative stress are known factors that can contribute to cardiovascular disease, including the development of high cholesterol and triglycerides.
Leptin Resistance: Leptin is a hormone that regulates appetite and metabolism. Hypothyroidism may be linked to leptin resistance, which can contribute to weight gain and metabolic disturbances, including elevated cholesterol and triglycerides.
Thyroid Hormones and Liver Function: Thyroid hormones influence liver function, and the liver is crucial for regulating cholesterol and triglyceride levels. In hypothyroidism, impaired thyroid function can affect the liver’s ability to properly manage lipids, potentially leading to elevated levels.

It’s important to note that while there is a connection between hypothyroidism and dyslipidemia, not everyone with hypothyroidism will necessarily experience high cholesterol or triglycerides. Additionally, individual responses can vary, and other factors such as diet, genetics, and lifestyle play important roles in lipid metabolism.

If you suspect thyroid issues or are experiencing symptoms of hypothyroidism, it’s essential to consult with a healthcare professional. They can perform appropriate tests and provide guidance on managing thyroid function and associated conditions.

What is LEPTIN RESISTANCE?

Leptin resistance is a condition in which the body’s cells become less responsive to the effects of the hormone leptin. Leptin is produced by fat cells and plays a key role in regulating appetite and energy expenditure. Its primary function is to signal to the brain that the body has enough stored fat, thereby influencing feelings of satiety and regulating metabolism.

When leptin resistance occurs, the brain no longer receives accurate signals about the body’s fat stores, leading to a disruption in the normal regulatory processes. This can contribute to overeating and weight gain. Several factors can contribute to the development of leptin resistance:

Obesity: Elevated levels of leptin are often found in individuals with obesity. Over time, the constant exposure to high levels of leptin may lead to decreased responsiveness, similar to how insulin resistance can develop in the context of chronic high insulin levels.
Inflammation: Inflammation in the body, often associated with conditions like obesity, can interfere with the proper functioning of leptin receptors. Inflammatory signaling pathways can disrupt the normal response to leptin.
Insulin Resistance: There is a connection between insulin and leptin signaling. Insulin resistance, a condition where cells become less responsive to the effects of insulin, may also contribute to leptin resistance.
Genetics: Genetic factors can influence an individual’s susceptibility to leptin resistance. Some people may be more predisposed to develop resistance based on their genetic makeup.
Lifestyle Factors: Poor diet, lack of physical activity, and other lifestyle factors can contribute to the development of leptin resistance. Diets high in refined sugars and saturated fats, for example, have been associated with an increased risk.

Leptin resistance can create a cycle where the body continues to store excess fat, and despite having high levels of leptin, the brain perceives a state of starvation, leading to increased appetite and decreased energy expenditure. This dysregulation of leptin signaling may contribute to difficulties in weight management and the development of obesity-related health issues.

Addressing leptin resistance often involves lifestyle modifications, including a healthy diet, regular physical activity, and weight management. In some cases, healthcare professionals may also consider medications or other interventions to address underlying factors contributing to leptin resistance. If someone suspects they may have leptin resistance or is struggling with weight management, it’s advisable to consult with a healthcare provider for a comprehensive evaluation and personalized recommendations.

How does liver congestion and gut health relate to low thyroid in functional medicine?

In functional medicine, practitioners often consider the interconnectedness of various body systems and how imbalances in one area can affect overall health. The relationship between liver congestion, gut health, and low thyroid function is complex and involves multiple pathways.

Here are some ways in which liver and gut health may be interconnected with thyroid health:

Liver Function and Thyroid Hormone Conversion: The liver plays a crucial role in the conversion of inactive thyroid hormone (T4) to active thyroid hormone (T3). T3 is the form of thyroid hormone that has the most biological activity. If the liver is congested or not functioning optimally, it may impact this conversion process, leading to lower levels of active thyroid hormone in the body. This can contribute to hypothyroidism or exacerbate existing thyroid dysfunction.
Detoxification Pathways: The liver is responsible for detoxifying various substances, including hormones. If the liver is overloaded with toxins or if its detoxification pathways are compromised, it may affect hormonal balance, including thyroid function. Supporting liver health is a common approach in functional medicine to address underlying issues contributing to thyroid dysfunction.
Gut Health and Nutrient Absorption: The health of the gut is crucial for nutrient absorption, including minerals important for thyroid function, such as iodine and selenium. A compromised gut lining, often referred to as “leaky gut” in functional medicine, can lead to malabsorption issues. This, in turn, may result in nutrient deficiencies that can impact thyroid health.
Inflammation and Autoimmunity: Both liver congestion and gut issues can contribute to inflammation. Chronic inflammation is associated with various autoimmune conditions, including autoimmune thyroid disorders like Hashimoto’s thyroiditis. In functional medicine, addressing the root causes of inflammation, whether they originate in the gut or liver, is a key component of managing thyroid health.
Microbiome and Immune Function: The gut microbiome plays a role in modulating the immune system. Imbalances in the gut microbiota can contribute to an overactive immune response, potentially leading to autoimmune conditions affecting the thyroid. Promoting a healthy gut microbiome through diet, probiotics, and other interventions is a common strategy in functional medicine.
Stress and Cortisol Regulation: Chronic stress can impact both the gut and the liver and can also affect thyroid function. The adrenal glands, which produce cortisol, are interconnected with thyroid function. Dysregulation of the stress response can contribute to hormonal imbalances, including those involving thyroid hormones.

In functional medicine, the focus is on identifying and addressing the underlying causes of health issues rather than just managing symptoms. This may involve assessing the health of the liver, addressing gut imbalances, supporting nutrient absorption, and considering lifestyle factors such as stress management. It’s important to note that individual responses can vary, and a personalized approach is often necessary in addressing these interconnected aspects of health. Consulting with a qualified healthcare professional, such as a functional medicine practitioner, can help determine the most appropriate interventions for an individual’s specific circumstances.

How does proper protein digestion and iodine levels impact thyroid health to get the right building blocks?

Protein digestion and iodine levels are both crucial factors in supporting thyroid health, as they contribute to the production and regulation of thyroid hormones.

Here’s how proper protein digestion and adequate iodine levels impact the thyroid:

Iodine and Thyroid Hormone Synthesis: Iodine is an essential mineral required for the synthesis of thyroid hormones. The thyroid gland takes up iodine from the bloodstream and incorporates it into the structure of thyroid hormones, primarily thyroxine (T4) and triiodothyronine (T3). These hormones are vital for regulating metabolism and maintaining overall health.
Thyroglobulin and Protein Digestion: Thyroid hormones are synthesized within the thyroid follicles by combining iodine with a protein called thyroglobulin. Proper protein digestion is essential for breaking down dietary proteins into amino acids, the building blocks of proteins. Amino acids are crucial for the synthesis of thyroglobulin, and any disruption in protein digestion can affect the availability of these building blocks.
Conversion of T4 to T3: While T4 is the primary thyroid hormone produced by the thyroid gland, it is relatively inactive. T3, on the other hand, is the more active form that exerts most of the biological effects of thyroid hormones. The conversion of T4 to T3 occurs mainly in peripheral tissues, including the liver and kidneys. Adequate protein intake is necessary for this conversion process, as certain amino acids, such as tyrosine and selenium-dependent selenocysteine, are involved.
Thyroid-Binding Proteins: Thyroid hormones are transported in the bloodstream bound to proteins, including thyroxine-binding globulin (TBG), transthyretin, and albumin. Proper protein digestion and amino acid availability are essential for the synthesis of these binding proteins, which help transport thyroid hormones to various tissues in the body.

To support thyroid health through nutrition, consider the following:

Iodine-Rich Foods: Include iodine-rich foods in your diet, such as seaweed, iodized salt, fish, dairy products, and eggs. Be mindful of iodine intake, as excessive amounts can also have negative effects.
Protein-Rich Foods: Ensure an adequate intake of high-quality protein sources to provide the necessary amino acids for thyroglobulin synthesis and the conversion of T4 to T3. Good sources include lean meats, poultry, fish, dairy, eggs, legumes, and nuts.
Nutrient-Rich Diet: In addition to iodine and protein, ensure a well-balanced diet that includes other essential nutrients for thyroid health, such as selenium, zinc, iron, and vitamins like B12 and D.

If you have concerns about your thyroid health or suspect deficiencies, it’s important to consult with a healthcare professional. They can assess your specific needs, conduct relevant tests, and provide personalized recommendations to support optimal thyroid function.

Which amino acids make thyroid hormones?

Thyroid hormones are primarily composed of the amino acid tyrosine, which serves as the building block for the synthesis of both thyroxine (T4) and triiodothyronine (T3). The process of thyroid hormone synthesis involves iodination of tyrosine residues within the protein thyroglobulin.

Here’s a simplified overview of the steps involved in thyroid hormone synthesis:

Iodination of Tyrosine: In the thyroid gland, iodine is actively taken up from the bloodstream and incorporated into the amino acid tyrosine, which is part of the protein thyroglobulin. This iodination occurs at specific sites on the tyrosine residues.
Formation of Thyroxine (T4) and Triiodothyronine (T3): Thyroxine (T4) is formed when two iodine molecules are added to tyrosine, and triiodothyronine (T3) is formed when three iodine molecules are added. These iodinated tyrosine residues are part of the thyroglobulin protein.
Release of Thyroglobulin and Hormone Activation: Thyroglobulin containing T4 and T3 is stored in the thyroid follicles. When the thyroid gland is stimulated, thyroglobulin is released into the bloodstream. Enzymes then cleave T4 and T3 from the thyroglobulin molecule, making them active and available for use in the body.

The amino acid tyrosine is crucial for the proper synthesis of thyroid hormones, and its availability depends on dietary intake. Tyrosine is a non-essential amino acid, meaning the body can synthesize it from phenylalanine, an essential amino acid obtained from dietary protein sources.

It’s important to note that while tyrosine is a key amino acid for thyroid hormone synthesis, other amino acids, such as cysteine, play a role in the structure of thyroglobulin and the formation of disulfide bonds within the protein.

A well-balanced diet that includes sufficient protein from various sources provides the necessary amino acids, including tyrosine, to support the synthesis of thyroid hormones. If there are concerns about thyroid function or nutritional status, it’s advisable to consult with a healthcare professional for a thorough evaluation and appropriate guidance.

TEST AND NOT GUESS about your health from the inside out!

Helicobacter pylori (H. pylori) is a type of bacteria that can infect the stomach lining and is known to be associated with various gastrointestinal conditions. While the direct impact of H. pylori on protein digestion and tyrosine metabolism is not fully understood, there are several indirect ways in which an H. pylori infection could potentially affect thyroid hormone production:

Impaired Absorption of Nutrients: H. pylori infection can lead to chronic inflammation in the stomach lining, potentially affecting the absorption of nutrients, including amino acids like tyrosine. If nutrient absorption is compromised, it could indirectly influence the availability of tyrosine for thyroid hormone synthesis.
Alteration of Stomach Acid Levels: H. pylori infection can influence stomach acid production. Changes in stomach acid levels may affect the breakdown of dietary proteins into amino acids during digestion. Adequate stomach acid is necessary for protein digestion, and alterations in this process may impact the availability of amino acids, including tyrosine.
Inflammation and Systemic Effects: Chronic inflammation resulting from H. pylori infection may have systemic effects, potentially affecting metabolic processes in the liver and other organs. Inflammation and systemic changes could indirectly impact the synthesis and metabolism of thyroid hormones.
Nutrient Deficiencies: Chronic H. pylori infection has been associated with nutrient deficiencies, including vitamins and minerals that are important for thyroid function. For example, deficiencies in selenium and zinc, which are essential for the conversion of thyroxine (T4) to triiodothyronine (T3), may impact thyroid hormone production and activity.

It’s important to note that the relationship between H. pylori infection, protein digestion, and thyroid function is complex and multifaceted. While some studies suggest associations between H. pylori infection and alterations in nutrient absorption or inflammation, the specific mechanisms and clinical implications are still areas of ongoing research.

If there are concerns about H. pylori infection or its potential impact on thyroid health, it’s advisable to consult with a healthcare professional. Testing for H. pylori and addressing any associated gastrointestinal issues would be part of a comprehensive approach to managing health. Additionally, addressing nutritional needs and supporting overall gut health may be important considerations in supporting thyroid function.