More reasons to TEST and not GUESS if you have the optimal levels of Vitamin D!

Are you taking Vitamin D3 each day -especially if you can’t get outside when the sun is shining above you onto your bare skin?

What you don’t hear from the media (a new blog idea!)

One Vitamin D research study…

An inadequate supply of vitamin D has a variety of skeletal and non-skeletal effects. There is ample evidence that various non-communicable diseases (hypertension, diabetes, CVD, metabolic syndrome) are associated with low vitamin D plasma levels. These comorbidities, together with the often concomitant vitamin D deficiency, increase the risk of severe COVID-19 events.

Much more attention should be paid to the importance of vitamin D status for the development and course of the disease. Particularly in the methods used to control the pandemic (lockdown), the skin’s natural vitamin D synthesis is reduced when people have few opportunities to be exposed to the sun. The short half-lives of the vitamin therefore make an increasing vitamin D deficiency more likely.

Specific dietary advice, moderate supplementation or fortified foods can help prevent this deficiency. In the event of hospitalisation, the status should be urgently reviewed and, if possible, improved.

Vitamin D and Genetics: VDR

VDR VDR (Vitamin D Receptor) encodes the nuclear hormone receptor for vitamin D3. Low or low normal vitamin D values are often seen in those with chronic illness and even the general population.

Low vitamin D is related to a lot of neurological and immunological conditions.

Vitamin D stimulates enzymes that create dopamine.

VDR Tak and VDR Bsm are usually inverse from eachother. So if there is a (+/+) VDR Tak, there would be a (-/-) VDR Bsm. However, this is not always the case. It has been clinically observed that the body may have trouble tolerating methyl donors with a COMT V158M + and a VDR Taq + status.

VDR Taq (-/-) individuals may already have higher levels of dopamine, and combinations of variations COMT and VDR Taq can lead to a wide range of dopamine levels.

Those that are VDR Taq (+/+) and COMT (-/-) may have lowest dopamine levels.

Okay, so the VDR Genetic SNP, the vitamin D receptor, may impact your dopamine levels but how does that impact your immune system?

Vitamin D and the Immune System

Vitamin D has important functions beyond those of calcium and bone homeostasis which include modulation of the innate and adaptive immune responses.

Vitamin D deficiency is prevalent in autoimmune disease.

Cells of the immune system are capable of synthesizing and responding to vitamin D. Immune cells in autoimmune diseases are responsive to the ameliorative effects of vitamin D suggesting that the beneficial effects of supplementing vitamin D deficient individuals with autoimmune disease may extend beyond effects on bone and calcium homeostasis.

Now what are you doing in these darker days to get your vitamin D levels up?

I am swimming in an outdoor pool at noon three days a week or biking in the afternoon – plus sitting outside to work in my new “outdoor office” when possible!

What are our the healthy optimal levels of Vitamin D?

Remember- more is not better. Homeostasis. The Goldilocks Effect for everything…not too little, not too much, just the right amount to create a positive effect or response.

Dr. James DiNicolantonio

Posted: Your nutrient status determines how well you fight off infections!

Low Vit D? = Worse COVID outcomes

  • Low selenium? = Worse COVID outcomes
  • Low zinc? = Worse COVID outcomes
  • Low Vit C? = Worse COVID outcomes

Low Vitamin D levels = Increased COVID-19 mortality!

Compared to Vit D levels of 30-40 or higher studies show

  • < 30 ng/mL = 2-3X death
  • < 12 ng/mL = 14.7X death
  • < 20 ng/mL vs. 55 ng/mL = 2X higher risk
  • Low vitamin D = increased risk of testing positive for COVID-19!

Make sure you are not vitamin D deficient!

The Immunity Fix…/dp/B08M1QXXF6

Open AccessArticle

Vitamin D Deficiency and Outcome of COVID-19 Patients

In summary, this observational study among patients with COVID-19 who have experienced a definite outcome shows an association between VitD status and severity of and mortality from COVID-19. Prospective, randomized controlled studies on VitD supplementation in SARS-CoV-2 infected individuals are highly warranted …






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